Table 4. Sensitivity analysis of pooled OR combining family-based and case-control studies for GSDMB rs7216389 polymorphism.
| Study omitted | OR (95% CIs) | χ2 | P* | P†heterogeneity |
|---|---|---|---|---|
| Tavendale R, 2008 | 1.36 (1.25-1.47) | 54.72 | <0.01 | <0.01 |
| Yang FF, 2012 | 1.36 (1.26-1.47) | 61.83 | <0.01 | <0.01 |
| Karunas AS, 2011 | 1.34 (1.25-1.44) | 64.91 | <0.01 | <0.01 |
| Yu J, 2011 | 1.38 (1.27-1.49) | 61.36 | <0.01 | <0.01 |
| Galanter J (A), 2008 | 1.37 (1.26-1.48) | 62.04 | <0.01 | <0.01 |
| Moffatt MF (G), 2007 | 1.36 (1.25-1.47) | 56.69 | <0.01 | <0.01 |
| Moffatt MF (B), 2007 | 1.35 (1.25-1.45) | 60.29 | <0.01 | <0.01 |
| Binia AD, 2011 | 1.36 (1.26-1.48) | 57.07 | <0.01 | <0.01 |
| Leung TF, 2009 | 1.37 (1.27-1.48) | 64.06 | <0.01 | <0.01 |
| Ferreira MA, 2011 | 1.38 (1.27-1.50) | 57.84 | <0.01 | <0.01 |
| Hirota T, 2008 | 1.36 (1.26-1.47) | 57.97 | <0.01 | <0.01 |
| Verlaan DJ (CR), 2009 | 1.36 (1.26-1.47) | 57.92 | <0.01 | <0.01 |
| Verlaan DJ (CA), 2009 | 1.38 (1.28-1.49) | 66.35 | <0.01 | <0.01 |
| Galanter J (P), 2008 | 1.39 (1.29-1.50) | 78.57 | <0.01 | <0.01 |
| Galanter J (M), 2008 | 1.39 (1.30-1.50) | 82.63 | <0.01 | <0.01 |
*DerSimonian and Laird random-effects model used to determine the significance of the overall OR; †Cochran's χ2-based Q statistic test used to assess the heterogeneity.
TDT, transmission/disequilibrium test; A, America; G, German; B, British; CR, Costa Rica; CA, CAMP; P, Puerto Ricans; M, Mexican.