Table 4. Anaqardia as a Traditional Antidementia Formulation, Probably Inhibiting Alzheimer’s Disease Pathology Through All Known Mechanisms (9) a.
Scientific Names | Persian Names | Part Used | Contribution, % | Mechanism of Action | ||||
---|---|---|---|---|---|---|---|---|
AChE Inhibitor | NMDA Blocker | Antioxidant | Anti-inflammatory | Aβ Inhibitor | ||||
Terminalia chebula | HalilehSiah | Fruit | 16.7 | √ | √ | |||
Terminalia belerica | Balileh | Fruit | 16.7 | √ | √ | |||
Embelica officinale | Amla | Fruit | 16.7 | √ | √ | |||
Nigella sativa | Siahdaneh | Seed | 11 | √ | √ | |||
B. bambos | Tabashir | Bark milk | 2.75 | √ | ||||
Eletaria cardamomum | Ghagheleh | Fruit | 3.2 | √ | ||||
Cyperus rotundus | So’d | Tuber | 2.75 | √ | √ | |||
Semecarpus anacardium | Belador | Nutshell oil | 2.75 | √ | √ | |||
Piper nigrum | Filfil-e Siah | Fruit | 5.5 | √ | √ | √ | √ | |
Piper longum | Darfilfil | Fruit | 5.5 | √ | √ | |||
Piper longum | Darfilfil | Root | 5.5 | √ | √ | |||
Zingiber officinale | Zanjabil | Rhizome | 5.5 | √ | √ | |||
Pimpinella anisum | Anisun | Fruit | 5.5 |
a Abbreviations: NMDA, N-methyl-D-aspartate; AChE, acetylcholine esterase.