Table 1.
Condition | Group 1 (n=89; IgA aB2GPI-Positive) | Group 2 (n=180; IgA aB2GPI-Negative) | P Value | ||
---|---|---|---|---|---|
N or Mean | SEM or Percent | N or Mean | SEM or Percent | ||
Sex (women) | 42 | 47.2% | 82 | 45.6% | 0.90 |
Weight (kg) | 67.2 | ±1.5 | 66.8 | ±1.0 | 0.81 |
Height (cm) | 163.5 | ±1.0 | 165.4 | ±0.7 | 0.16 |
Age (yr) | 55.9 | ±1.3 | 47.9 | ±1.0 | <0.001 |
Donor age (yr)a | 53.1 | ±2.0 | 43.5 | ±1.4 | <0.001 |
Time on dialysis (mo) | 27.7 | ±3.1 | 37.1 | ±3.7 | 0.10 |
Peritoneal dialysis | 14 | 15.7% | 24 | 13.3% | 0.73 |
Causes of CKD | |||||
Chronic GN | 18 | 20.2% | 51 | 28.3% | 0.20 |
Interstitial kidney disease | 20 | 22.5% | 33 | 18.3% | 0.52 |
Nephroangiosclerosis | 5 | 5.6% | 21 | 11.7% | 0.17 |
Polycystic kidney disease | 15 | 16.9% | 29 | 16.1% | 0.98 |
Diabetes | 11 | 12.4% | 13 | 7.2% | 0.25 |
Unknown | 11 | 12.4% | 14 | 7.8% | 0.32 |
Other | 9 | 10.1% | 19 | 10.6% | 0.92 |
Pretransplant | |||||
Severe thrombosis before transplantb | 10 | 11.2% | 7 | 3.9% | 0.04 |
Stroke | 3 | 3.4% | 1 | 0.6% | 0.12 |
Peritoneal dialysis | 14 | 15.7% | 24 | 13.3% | 0.73 |
Dyslipidemia | 23 | 25.8% | 62 | 34.4% | 0.20 |
Diabetes mellitus | 14 | 15.7% | 17 | 9.4% | 0.19 |
Previous transplant | 3 | 3.4% | 34 | 18.9% | 0.001 |
Double renal transplant | 9 | 10.1% | 13 | 7.2% | 0.56 |
PRA>50% (at time of transplant) | 3 | 3.4% | 6 | 3.3% | 0.73 |
Historical PRA>50% | 9 | 10.1% | 28 | 15.6% | 0.30 |
Cold ischemia (h) | 20.7 | ±0.6 | 19.8 | ±0.4 | 0.18 |
Warm ischemia in recipient (min) | 31.0 | ±0.7 | 31.1 | ±0.5 | 0.91 |
Donor age is a recipient age-dependent variable.
Excluding vascular access.