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. 2015 Feb 26;9:18. doi: 10.3389/fnsys.2015.00018

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Copyright © 2015 Bojak, Stoyanov and Liley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Snapshot of the h_e activity of the cortical surface at simulation time 54.94 s under the influence of 1 MAC isoflurane. Black arrows with labels “a,” “b,” and “c” point to the cortical locations of the time series shown in the other panel. Note the toroidal boundaries, e.g., the circular burst front that appears cut off around (x,y) = (44.8, 0) cm continues at x = (44.8, 51.2) cm. (B) Time series of h_e (blue) and Γ_ee (green) taken from the three different positions marked as “a,” “b,” and “c” in the other panel. It is obvious that bursts are not generally synchronized in time at the different positions. Spatiotemporal correlations from propagating “burst waves” can occur, but are removed at larger distances by the interference from other emergent patterns. An animation of this simulation is provided as Movie 1 in the Supplementary Material.