FIG. 7.

[³H]fluconazole uptake with and without ergosterol (erg) or growth under conditions of low oxygen tension (−O₂). Bars indicate standard errors of the mean. (A) The level of uptake by wild-type strain Cg1660 was low under all conditions. Note that two of the three lines for Cg1660 overlap. For all conditions the level of uptake was higher in Cgerg1 mutant CgTn201S and was not restored to wild-type levels by ergosterol under aerobic conditions or conditions of low oxygen tension. (B) The level of [³H]fluconazole uptake by CgTn201S was lowered nearly to wild-type levels by CgERG1 complementation (CgTn201C).