TABLE 2.
BAL5788 dosea (mg) and study day | Urine collection interval (h) | Maximum BAL9141 concn in urine (μg/ml) | Cumulative 24-h recovery of BAL9141 in urine (% of dose)b |
---|---|---|---|
500 | |||
1 | 0-2 | 1,406 | 82.2 (70.5-94.8) |
2-4 | 220 | ||
8 | 0-2 | 800 | 87.8 (76.9-104.2) |
2-4 | 293 | ||
750 | |||
1 | 0-2 | 2,540 | 83.7 (76.0-87.1) |
2-4 | 169 | ||
8 | 0-2 | 2,060 | 84.4 (73.1-100.2) |
2-4 | 331 |
Doses are expressed as equivalent milligrams of BAL9141.
The values are arithmetic means (ranges).