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Doses, times that plasma drug concentrations exceeded the MIC, and T > MIC on day 1 and day 8
| BAL5788 dosea (mg) | Time (h) the plasma BAL9141 concn exceeded the MICb
|
T > MIC (% of 12-h dosing interval)
|
||
|---|---|---|---|---|
| Total | Unbound | Total | Unbound | |
| 500 | 6 | 5 | 50 | 42 |
| 750 | 7 | 6 | 58 | 50 |
Doses are expressed as equivalent milligrams of BAL9141.
The MIC is 4 μg/ml.
