FIG. 5.
Effect of oral phage on the introduction of ampicillin-resistant E. coli in mice. (A) Fecal cell counts in three mice force-fed with 5 × 107 CFU of ampicillin-resistant E. coli and ampicillin (A/E) at the time points marked with an arrow below the time axis. The ordinate shows the logarithm of CFU per gram of stool. Each vertical bar represents the fecal cell count for one animal at the specified time point. (B) The same experiment as depicted in panel A except that in addition to ampicillin the mice also received the phage cocktail at 106 PFU/ml in the drinking water. The rightmost black data points refer to a control mouse not receiving ampicillin-resistant E. coli.