Table II.
F ratios and associated P values for various parameters studies for CCR5−/− and WT mice by time points
| Time point | Effects | Summed OA score |
Max OA score |
Synovium | BV/TV | CDI | SMI | Tb.N. | Tb.Th. | Tb.Sp. | Subchondral bone thickness |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 weeks | Genotype | F = 0.016 | F = 0.618 | F = 0.716 | F = 0.036 | F = 0.141 | F = 0.249 | F = 0.385 | F = 0.840 | F = 0.026 | F = 1.870 |
| P = 0.900 | P = 0.439 | P = 0.405 | P = 0.848 | P = 0.708 | P = 0.619 | P = 0.537 | P = 0.363 | P = 0.870 | P = 0.182 | ||
| Procedure | F = 17.124 | F = 8.584 | F = 0.373 | F = 0.022 | F = 2.504 | F = 2.866 | F = 0.003 | F = 1.518 | F = 0.034 | F = 6.112 | |
| P < 0.001 | P = 0.006 | P = 0.546 | P = 0.880 | P = 0.119 | P = 0.095 | P = 0.953 | P = 0.223 | P = 0.852 | P = 0.019 | ||
| Genotype*procedure | F = 1.689 | F = 1.939 | F = 0.247 | F = 1.057 | F = 2.267 | F = 0.083 | F = 0.179 | F = 5.241 | F = 0.233 | F = 0.015 | |
| P = 0.205 | P = 0.175 | P = 0.623 | P = 0.308 | P = 0.137 | P = 0.774 | P = 0.673 | P = 0.025 | P = 0.630 | P = 0.901 | ||
| 8 weeks | Genotype | F = 7.267 | F = 1.531 | F = 1.680 | F = 5.022 | F = 1.127 | F = 4.149 | F = 0.722 | F = 1.487 | F = 0.919 | F = 9.173 |
| P = 0.011 | P = 0.224 | P = 0.203 | P = 0.029 | P = 0.292 | P = 0.046 | P = 0.398 | P = 0.227 | P = 0.341 | P = 0.005 | ||
| Procedure | F = 63.105 | F = 75.004 | F = 14.046 | F = 0.282 | F = 5.633 | F = 1.116 | F = 0.497 | F = 5.185 | F = 0.225 | F = 19.570 | |
| P < 0.001 | P < 0.001 | P = 0.001 | P = 0.597 | P = 0.021 | P = 0.295 | P = 0.483 | P = 0.026 | P = 0.636 | P < 0.001 | ||
| Genotype*procedure | F = 3.820 | F = 1.808 | F = 0.678 | F = 2.151 | F = 0.127 | F = 1.026 | F = 0.344 | F = 0.110 | F = 0.145 | F = 0.756 | |
| P = 0.058 | P = 0.187 | P = 0.415 | P = 0.148 | P = 0.722 | P = 0.315 | P = 0.559 | P = 0.740 | P = 0.704 | P = 0.391 | ||
| 12 weeks | Genotype | F = 1.662 | F = 0.030 | F = 0.584 | F = 5.959 | F = 0.002 | F = 12.731 | F = 0.141 | F = 8.047 | F = 0.151 | F = 0.596 |
| P = 0.222 | P = 0.865 | P = 0.458 | P = 0.040 | P = 0.958 | P = 0.007 | P = 0.716 | P = 0.021 | P = 0.707 | P = 0.462 | ||
| Procedure | F = 5.306 | F = 5.435 | F = 14.428 | F = 0.092 | F = 6.802 | F = 3.337 | F = 2.907 | F = 7.316 | F = 1.648 | F = 25.507 | |
| P = 0.040 | P = 0.038 | P = 0.002 | P = 0.768 | P = 0.031 | P = 0.105 | P = 0.126 | P = 0.026 | P = 0.235 | P < 0.001 | ||
| Genotype*procedure | F = 5.304 | F = 1.453 | F = 3.180 | F = 0.403 | F = 0.023 | F = 0.000 | F = 0.133 | F = 2.302 | F = 0.077 | F = 0.001 | |
| P = 0.040 | P = 0.251 | P = 0.097 | P = 0.543 | P = 0.881 | P = 0.984 | P = 0.724 | P = 0.167 | P = 0.787 | P = 0.972 |
BV/TV = trabecular bone volume fraction, the ratio of trabecular bone volume over endocortical total volume; CDI = connectivity density index, SMI = structure model index, Tb.N. = trabecular number, Tb.Th. = trabecular thickness, Tb.Sp. = trabecular separation.
Bold values indicate statistical significance at P < 0.