FIG. 2.

Oral treatment dose titration of BMS-433771 in cotton rats (A) and BALB/c mice (B). Single oral doses of BMS-433771 were given by gavage to cohorts of six animals 1 h prior to intranasal inoculation of Long strain. The cohorts are shown on the abscissa; the bar for the animal group inoculated with virus but not treated with BMS-433771 is labeled Control. Infectious RSV titers of each respective cohort are presented as bars on the ordinate, as percentages of the geometric mean viral titer (log₁₀ TCID₅₀ per gram of lung) of the control group. The geometric mean RSV titer for each respective cohort is listed as the number in parentheses.