Table 3.

Lipid measures by resolution of NASH at 96 weeks

	Resolution of NASH at 96 weeks
Mean(95% CI)	Resolved (N=52)	Not resolved (N=69)	P*	Adjusted P†
Non HDL-C(mg/dL)
Baseline	137.3(127.4,147.2)	140.1(130.9,149.2)	0.69	0.71
96 weeks	130.0(120.1,139.9)	141.2(131.7,150.7)	0.11	0.05
Change from baseline	−7.3(−14.9,0.2)	1.1(−5.7,7.9)	0.1	0.01
Triglycerides(mg/dL)
Baseline	139.7(113.7, 165.7)	152.5(127.4, 177.5)	0.49	0.72
96 weeks	161.4(132.3,190.6)	171.4(148.0,194.7)	0.59	0.3
Change from baseline	21.7(−2.2,45.6)	18.9(−1.7,39.5)	0.86	0.28
HDL(mg/dL)
Baseline	39.1(36.7,41.6)	36.5(34.3,38.7)	0.12	0.09
96 weeks	36.4(34.5,38.4)	34.5(32.8,36.2)	0.14	0.07
Change from baseline	−2.7(−4.5,−0.8)	−2.0(−3.6,−0.4)	0.56	0.42
LDL(mg/dL)
Baseline	110.8(101.5,120.2)	109.0(102.5,115.4)	0.73	0.97
96 weeks	99.8(90.6,109.1)	107.7(99.5,115.8)	0.21	0.16
Change from baseline	−11.2(−19.1,−3.3)	−2.1(−7.6,3.4)	0.05	0.06
Total cholesterol(mg/dL)
Baseline	176.4(166.0, 186.9)	176.6(166.8, 186.3)	0.99	0.96
96 weeks	166.4(156.5, 176.3)	175.7(165.8, 185.6)	0.2	0.11
Change from baseline	−10.0(−18.0,−2.0)	−0.9(−8.0,6.3)	0.09	0.02
Triglycerides/HDL
Baseline	4.0(3.0,5.0)	4.4(3.7,5.1)	0.48	0.62
96 weeks	4.8(3.8,5.9)	5.1(4.4,5.7)	0.69	0.31
Change from baseline	0.9(0.2,1.5)	0.7(0.04,1.3)	0.72	0.35

^*P-values derived from univariable linear regression models.

^†Adjusted p-values derived from linear regression models and included treatment group, baseline BMI, ethnicity, and for change measures, the baseline value of the lipid measure