Table 1.
Demographic, anthropometric and laboratory values for children with NAFLD in the Vitamin D study
| Characteristics | All Children (N=102) |
|---|---|
| Specimen characteristic: | |
| Vitamin D level | 23.1 ± 8.8 |
| Season: Spring/summer (Apr–Sept) | 68 (67%) |
| Demographics: | |
| Gender: Boys | 83 (81%) |
| Age at enrollment (years), mean±SD | 12.9 ± 2.7 |
| Caucasian: Yes | 74 (73%) |
| Hispanic: Yes | 71 (70%) |
| Region: South | 57 (56%) |
| Anthropometric: | |
| Tanner stage: early (1–2) | 63 (62%) |
| Tanner stage, mean±SD | 1.41 ± 2.4 |
| Body Mass Index (Z-score): | |
| < 2.0 (overweight or less) | 15 (15%) |
| 2.0 – (moderately or severely obese ) | 87 (85%) |
| Mean±SD | 2.40 ± 0.50 |
| Weight, kg, (mean±SD) | 86 ± 23 |
| Waist circumference, cm, (mean±SD) | 107 ± 14 |
| Laboratory values† (mean±SD): | |
| ALT (U/L) | 115 ± 68 |
| AST (U/L) | 67 ± 37 |
| GGT (U/L) | 48.5 ± 36.7 |
| Glucose (mg/dL) | 88.8 ± 8.4 |
| Insulin (mcU/mL) | 32.2 ± 17.6 |
| HOMA-IR (mg/dL × mcU/mL/405) | 7.1 ± 4.1 |
| Triglycerides (mg/dL) | 141.5 ± 89.5 |
| Cholesterol, total (mg/dL) | 168.6 ± 31.6 |
| Cholesterol, HDL (mg/dL) | 36.7 ± 7.2 |
| Cholesterol, LDL (mg/dL) | 105.3 ± 26.0 |
*
106 participants age 2 through 18 at enrollment in NAFLD DB or TONIC with histology from centrally reviewed biopsies within 31 days of blood draw were analyzed for Vitamin D level. A total of 102 participants had a Vitamin D level.
No. (%) or mean±SD are presented.
†
Variable definitions:
ALT: alanine aminotransferase, AST: aspartate aminotransferase, GGT: gamma glutamyl trans-peptidase, HOMA-IR: homeostatis model assessment of insulin resistance index