. Author manuscript; available in PMC: 2015 Feb 26.

Published in final edited form as: Am J Gastroenterol. 2014 Nov 11;109(12):1881–1890. doi: 10.1038/ajg.2014.327

Table 3.

Kaplan–Meier estimate of median survival and survival rate of pCCA patients classified by the proposed staging system

Stage	Number of death/total	Median survival (months)	1-Year Kaplan–Meier estimate (95% CI)	5-Year Kaplan–Meier estimate (95% CI)	Univariate HR (95% CI)	P	Univariate HR (95% CI) from treatment strata model	P
I	39/76	48.6	87.9% (80.8–95.6)	45.3% (34.6–58.9)	1.00 (Reference)	<0.0001	1.00 (Reference)	<0.0001
II	62/101	21.8	69.4% (60.4–79.8)	27.9% (19.6–39.8)	1.80 (1.20–2.68)	0.0043	1.72 (1.15–2.58)	0.0087
III	129/164	8.6	36.1% (28.9–45.0)	2.8% (0.8–9.9)	5.12 (3.52–7.45)	<0.0001	3.08 (2.03–4.57)	<0.0001
IV^a	51/58	2.8	8.1% (3.2–20.6)	—	16.60 (10.52–26.22)	<0.0001	8.67 (5.20–14.56)	<0.0001

HR, hazard ratio; pCCA, perihilar cholangiocarcinoma; 95% CI, 95% confidence interval.

3-Month and 6-month survival rates of stage IV patients were 46.4% and 22.2%, respectively.