Table 5. Unifactorial and multifactorial associations of tertile of Trust research funding, patient recruitment to studies, structures and processes with risk adjusted mortality.

		Unifactorial	Multifactorial
Resource measure by tertile		Odds Ratio of Death (Confidence interval)	Odds Ratio of Death (Confidence interval)
Research funding	Lowest	1.156 (1.144–1.168) p<0.0001	1.050 (1.033–1.068) p<0.0001
	Middle	1.135 (1.123–1.147) p<0.0001	1.040 (1.024–1.055) p<0.0001
	Highest	1	1
	Lowest	1.056 (1.043–1.068) p<0.0001	1.069 (1.052–1.086) p<0.0001
Patients recruited to studies	Middle	1.056 (1.044–1.069) p<0.0001	1.085 (1.070–1.100) p<0.0001
	Highest	1	1
Total doctor staffing	Lowest	1.152 (1.140–1.164) p<0.0001	1.089 (1.069–1.109) p<0.0001
	Middle	1.098 (1.086–1.109) p<0.0001	1.061 (1.047–1.076) p<0.0001
	Highest	1	1
Total nurse staffing	Lowest	1.100 (1.089–1.112) p<0.0001	0.960 (0.944–0.975) p<0.0001
	Middle	1.038 (1.028–1.048) p<0.0001	0.985 (0.973–0.998) p = 0.0001
	Highest	1	1
Total critical care beds	Lowest	1.060 (1.050–1.072) p<0.0001	0.964 (0.951–0.978) p<0.0001
	Middle	1.065 (1.054–1.076) p<0.0001	1.006 (0.993–1.020) p = 0.3888
	Highest	1	1
Total radiodiagnostics	Lowest	1.096 (1.086–1.107) p<0.0001	1.036 (1.022–1.050) p<0.0001
	Middle	1.068 (1.058–1.079) p<0.0001	1.055 (1.043–1.067) p<0.0001
	Highest	1	1
Operating theatres	Lowest	1.129 (1.119–1.140) p<0.0001	1.064 (1.049–1.079) p<0.0001
	Middle	1.084 (1.073–1.094) p<0.0001	1.034 (1.022–1.047) p<0.0001
	Highest	1	1
Operational expenditure	Lowest	1.158 (1.146–1.170) p<0.0001	1.044 (1.028–1.061) p<0.0001
	Middle	1.093 (1.082–1.104) p<0.0001	1.012 (0.999–1.026) p = 0.0792
	Highest	1	1
Teaching hospital status	Non-teaching	1.076 (1.066–1.086) p<0.0001	0.956 (0.942–0.971) p<0.0001
	Teaching	1	1

Of note the association between research funding, patient recruitment and mortality persists in the multifactorial model. The goodness of fit c-statistic (area under the receiver operating characteristic curve) for the multifactorial model is 0.81.