TABLE 1:

Results of the Mouse Signal Transduction Pathway Finder RT² Profiler PCR Array.

Gene symbol	Gene name	Expression, fold change vs. WT
Bmp2	Bone morphogenetic protein 2	2.33
Bmp4	Bone morphogenetic protein 4	3.00
Ccl2	Chemokine (C-C motif) ligand 2	−1.56
Cdkn2a	Cyclin-dependent kinase inhibitor 2A	−1.58
Cxcl1	Chemokine (C-X-C motif) ligand 1	−2.53
Egr1	Early growth response 1	1.79
Fn1	Fibronectin 1	−2.02
Hhip	Hedgehog-interacting protein	2.79
Il1a	Interleukin 1α	1.65
Il4ra	Interleukin 4 receptor α	−1.75
Mmp10	Matrix metallopeptidase 10	−1.91
Pparg	Peroxisome proliferator–activated receptor γ	2.53
Selp	Selectin, platelet	−3.82
Tcf7	Transcription factor 7, T-cell specific	3.21
Tfrc	Transferrin receptor	1.69
Pmepa1	Prostate transmembrane protein, androgen induced 1	−1.56
Vcam1	Vascular cell adhesion molecule 1	1.54
Vegfa	Vascular endothelial growth factor A	1.52
Wisp1	WNT1-inducible signaling pathway protein 1	1.89

Genes of interest were identified as those whose expression was changed 1.5-fold or greater in Gja1^Jrt/+ vs. WT samples. RNA was isolated from trabecular bone of 2-mo-old WT and Gja1^Jrt/+ mice; n = 2, and each sample was the combination of n ≥ 2 independent biological samples.