TABLE 2.

Times to achieve 50, 90, 99, and 99.9% reductions in growth from starting inoculum with 2 μg of amphotericin B per ml

Isolate (no. of isolates)	t50 (h)		t90 (h)		t99 (h)		t99.9 (h)
	Range	Mean ± SD	Range	Mean ± SD	Range	Mean ± SD	Range	Mean ± SD
C. albicans (6)	0.10-0.22	0.16 ± 0.06	0.36-0.74	0.55 ± 0.19	0.72-1.47	1.09 ± 0.39	1.08-2.20	1.64 ± 0.58
C. dubliniensis (3)	0.10-0.11	0.11 ± 0.005	0.36-0.39	0.122 ± 0.43	0.72-0.78	0.75 ± 0.03	1.08-1.17	1.13 ± 0.05
C. glabrata (4)	1.23-0.11	0.56 ± 0.47	0.36-4.10	1.85 ± 1.57	0.72-8.21	3.74 ± 3.12	1.07-12.32	5.61 ± 4.68
C. krusei (5)	2.55-5.47	4.27 ± 1.45	8.49-18.18	14.18 ± 4.84	16.99-36	28.37 ± 9.69	25.48-54.55	42.55 ± 14.53
C. lusitaniae (3)	0.21-0.61	0.35 ± 0.23	0.72-2.04	1.16 ± 0.76	1.44-4.08	2.32 ± 1.51	2.16-6.11	3.48 ± 2.27
C. parapsilosis (5)	0.81-4.83	2.71 ± 1.53	2.71-16.07	8.99 ± 5.09	5.43-32.13	17.99 ± 10.19	8.15-48.20	26.99 ± 15.29
C. tropicalis (3)	5.28-6.15	5.82 ± 0.47	17.85-20.46	19.33 ± 1.56	35.10-40.92	38.67 ± 3.12	52.65-61.38	58.01 ± 4.68
C. lusitaniae ATCC 200950a		5.04		16.7		33.5		>48
C. lusitaniae ATCC 200951a		4.42		14.7		29.4		>48
C. lusitaniae ATCC 200952a		3.78		12.38		24.4		>48
C. lusitaniae ATCC 200953a		0.33		1.10		22		>48
C. albicans ATCC 200955a		4.99		16.6		33.21		>48
C. tropicalis ATCC 200956a		>48		>48		>48		>48
C. albicans ATCC 90028		0.65		2.17		4.34		6.5
C. krusei ATCC 6254		1.3		4.34		8.69		13.1
C. parapsilosis ATCC 22019		0.7		1.36		4.72		7.08

^aAmphotericin B-resistant strains.