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. Author manuscript; available in PMC: 2015 Dec 15.
Published in final edited form as: Cancer Res. 2014 Sep 19;74(24):7583–7598. doi: 10.1158/0008-5472.CAN-14-1235

Table 1.

Pearson correlation coefficients were measured between each gene or protein and FDG uptake in 30 tumors, irrespective of genotype (All tumors), or within the 6 tumors of each indicated genotype (Within genotype). Correlations that are statistically significant (p<0.05) are shown in red, and correlations that are marginally significant (p<0.1) are in bold.

Gene/Protein All
tumors
Within genotype
Akt Myc Wnt Ras Neu
Glut1 mRNA −0.077 −0.323 0.166 0.227 −0.426 −0.562
Glut1 protein 0.276 0.920 −0.244 −0.447 −0.613 0.942
HK1 mRNA −0.210 −0.315 −0.302 −0.602 0.700 −0.077
HK2 mRNA 0.270 0.541 0.210 0.759 −0.080 0.256
HK2 protein 0.585 0.463 0.196 0.567 −0.299 0.549
Glut4 protein 0.119 0.311 −0.148 −0.556 0.190 0.414
p-mTOR 0.191 0.141 0.015 −0.194 −0.549 0.754
p-S6 0.185 0.136 0.238 0.115 0.234 0.622
p-AMPK 0.355 0.879 0.332 −0.490 −0.719 −0.693
PFK-1 mRNA −0.176 −0.131 0.226 0.693 −0.199 0.224
PFK-2a mRNA 0.385 0.733 0.086 −0.151 0.041 −0.051
PFK-2b mRNA −0.369 −0.363 −0.666 −0.116 0.674 0.273
Slc2a4 (Glut4) −0.025 0.373 −0.117 −0.814 −0.261 −0.130
Slc5a1 (SLGT1) −0.415 −0.582 −0.583 0.788 0.161 0.263
Slc2a9 (Glut9) −0.149 −0.373 0.228 0.173 −0.564 0.292
Slc2a8 (Glut8) −0.163 0.137 −0.680 0.059 0.389 0.004
Slc2a10 (Glut10) −0.180 0.790 0.252 0.001 −0.131 −0.124
Slc2a12 (Glut12) −0.089 −0.436 −0.719 0.140 0.847 −0.327
Slc2a6 (Glut6) 0.059 −0.453 0.129 −0.012 −0.472 −0.159
p-PFK2b −0.363 −0.677 −0.087 −0.167 0.402 −0.252
Proliferation
(% Ki67+)
0.401 0.130 0.002 0.173 −0.097 0.222
HIF-1α 0.344 0.564 −0.210 −0.522 −0.472 −0.089