FIG. 3.

Parasite endocytosis of FITC-dextran from preloaded RBCs. RBCs preloaded with FITC-dextran and infected with parasites were left untreated (A) or were treated with chloroquine (B), artemisinin (C), or mefloquine (D) for 12 h. The pRBCs were subsequently immobilized on glass coverslips, rinsed in saponin, fixed, and viewed by fluorescence microscopy. Left panels, fluorescence images; right panels, corresponding phase-contrast images. Arrows denote the locations of the food vacuole, as indicated by the presence of the prominent hemozoin crystal.