Table 2.
Aqueous ethanol extracts of propolis (EEP) | IC50 (μg/mL) | ||
---|---|---|---|
Baker's yeast alpha-glucosidase | Rat intestinal sucrase | Rat intestinal maltase | |
WEP | 16.0 ± 1.38bc | 37.91 ± 0.52ab | 32.67 ± 0.24e |
25% EEP | 11.32 ± 2.23ab | 40.25 ± 0.97ab | 44.80 ± 0.25d |
50% EEP | 12.90 ± 1.14b | 53.12 ± 0.95b | 100.60 ± 2.95b |
75% EEP | 7.24 ± 1.16a | 32.34 ± 0.61a | 71.82 ± 2.95c |
95% EEP | 16.26 ± 0.43bc | 32.91 ± 0.54a | 102.76 ± 1.47b |
100% EEP | 20.01 ± 1.54c | 38.06 ± 0.56ab | 131.12 ± 1.83a |
Acarbose | 177.47 ± 6.28d | 538.30 ± 26.69c | 22.46 ± 0.86f |
Note: Water extracts of propolis were expressed as WEP. Extracts of propolis using 25%, 50%, 75%, 95%, and 100% (in water, v/v) aqueous ethanol solvents were expressed as 25% EEP, 50% EEP, 75% EEP, 95% EEP, and 100% EEP, respectively. Dates are mean ± standard deviation (n = 3). Values in the same column followed by the same lower case letter are not significantly different by Duncan's multiple range test (P < 0.05). Inhibition of propolis extracts against yeast and rat intestinal alpha-glucosidase were both expressed as IC50 (concentration of total phenolics able to scavenger 50% of alpha-glucosidase activity).