Table 2.

Survival analysis of grade 1 and 3 tumors classified with fuzzy molecular and histologic grades

fuzzy Gene Signature	HG 1&3 patients	fuzzy Gene Signatures		Histologic grade
	n	Hazard Ratio (95% CI)	p value logrank test	Hazard Ratio (95% CI)	p value logrank test
f MG A
NKI2 training	113	2.136 (1.466 - 3.113)	<.001	1.5896 (1.135 - 2.213)	<0.0052
NKI2 validation all	163	1.989 (1.463 - 2.704)	<.001	1.694 (1.294 - 2.218)	<.001
f MG B
KJX64/KJ125 training	99	1.923 (1.342 - 2.754)	<.001	1.546 (1.075 - 2.223)	<0.0184
Transbig	113	1.435 (1.005 - 2.051)	<0.0426	1.062 (0.792 - 1.426)	=0.0541
Stockholm	89	2.711 (1.313 - 5.595)	<0.00158	2.104 (1.28 - 3.459)	<0.0103
Pool 1	272	1.59 (1.25 to 2,02)	<0.0001	1.55 (1.20 to 2.00)	<0.001
f MG C
Uppsala training	123	1.484 (1.091 - 2.017)	<0.0103	1.773 (1.306 - 2.408)	<.001
Stockholm	89	4.134 (1.518 - 11.258)	<.001	2.104 (1.28 - 3.459)	<0.0103
f MG D
Transbig Training	113	1.28 (0.852 - 1.923)	=0.23	1.062 (0.792 - 1.426)	=0.0541
KJX64/KJ125	122	1.591 (1.157 - 2.186)	<0.00312	1.518 (1.11 - 2.077)	<0.00725
Stockholm	89	3.844 (1.412 - 10.469)	<.001	2.104 (1.28 - 3.459)	<0.0103
Pool 2	281	1.65 (1.31 to 2,07) supp KJX	<0.00001	1.66 (1.32 to 2.09)	<0.00001

Pool 1: Uppsala + Transbig + Stockholm.

Pool 2: KJX64/KJ125 + Uppsala + Stockholm.