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. 2015 Feb 26;10(2):e0117501. doi: 10.1371/journal.pone.0117501

Fig 2. Effect of ESa on carrageenan-induced edema and neutrophil migration and on lipopolysaccharide-induced fever.

Fig 2

Animals were treated with ethanolic extract form S. aggregata (ESa, 10 to 100 mg/kg, as indicated), Dexamethasone (Dex, 1 mg/kg), or the appropriate vehicles (Veh) by oral route. One hour after the oral treatment animals were injected with carrageenan (Cg, 300 μg) in the paw (panels A and B) or LPS (100 μg/kg, i.p, panel C). On panel B, the control (C) animals are non-injected animals. Data show the mean ± s.e.mean of the change in the paw thickness (μm, panel A), optical density (D.O./mg protein, panel B) or body temperature (°C, panel C) (n = 7–14). Symbols denote statistical difference in relation to the control (C) or Veh/Sal group (* P<0.05, **P<0.01) or to Veh/Cg (#p<0.05).