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. 2015 Feb 14;15:21. doi: 10.1186/s12862-015-0302-8

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© Kweon et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Genomic islands (GIs, large-genomic regions that contain multiple genes of probable horizontal origin) analysis of the PAH-degrading mycobacteria. (A) Comparison of the GIs from the PAH-degrading mycobacteria, depending upon core and dispensable genes. (B) HGT contribution of the 2,878 GI-located genes to the pan-genome of PAH-degrading mycobacteria. (C) Functional distribution of the 754 horizontally transferred genes to the core-genome based on COG. (D) Functional annotation of the horizontally transferred PAH-catabolic genes with respect to the general scheme of PAH metabolism proposed for M. vanbaalenii PYR-1. Only the 22 genes involved in RCP and SCP are shown. Please see reference [9] for a more detailed explanation of the general scheme of mycobacterial PAH metabolism.