Table 2. T-cell cytokine expression is often higher in CSF than in peripheral blood.
| Condition | Cell/marker | Median% CSF | Median% PBMC | Wilcoxon (paired) (sqrt) * p = |
|---|---|---|---|---|
| Constitutive | CD4+CD107a+ | 0.53 | 0.32 | 0.2534 |
| HIVp24 | CD4+CD107a+ | 0.69 | 0.30 | 0.0409 |
| Constitutive | CD4+TNFα+ | 2.09 | 0.26 | .0007 |
| HIVp24 | CD4+TNFα+ | 2.90 | 0.60 | <.0001 |
| Constitutive | CD4+IFNγ+ | 1.41 | 0.18 | <.0001 |
| HIVp24 | CD4+IFNγ+ | 2.18 | 0.34 | <.0001 |
| Constitutive | CD4+IL-2+ | 2.30 | 0.39 | <.0001 |
| HIVp24 | CD4+IL-2+ | 3.20 | 0.41 | <.0001 |
| Constitutive | CD8+CD107a+ | 0.12 | 0.12 | 0.3575 |
| HIVp24 | CD8+CD107a+ | 0.32 | 0.23 | 0.4723 |
| Constitutive | CD8+TNFα+ | 0.43 | 0.18 | 0.1616 |
| HIVp24 | CD8+TNFα+ | 0.51 | 0.17 | 0.0474 |
| Constitutive | CD8+IFNγ+ | 0.91 | 0.30 | 0.0007 |
| HIVp24 | CD8+IFNγ+ | 1.02 | 0.31 | 0.0002 |
| Constitutive | CD8+Il-2+ | 1.48 | 0.27 | 0.0002 |
| HIVp24 | CD8+Il-2+ | 2.30 | 0.26 | <.0001 |
*For analysis, percent positive values were square-root transformed