Table 7. The most significant predictor of neurocognitive decline was higher CD8+IFNγ response to HIV p24 antigen at baseline.

Measure	Stable/ Improved (10) (BL Median)	Declined (6) (BL Median)	t-Test p =
CD4 in PL	450	317	0.12
CD4/CD8 in PL	0.44	0.27	0.18
*%CD4+ in CSF	5.4	3.6	0.07
CSF RNA >40	50%	100%	0.09
*cCD8+IFNγ+	0.69	1.79	0.10
*cCD8+Il-2+	0.85	2.66	0.10
* p24.CD8+IFNγ+	0.73	1.56	0.02

c = constitutive

*square root transformed