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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Ther Drug Monit. 2015 Apr;37(2):236–245. doi: 10.1097/FTD.0000000000000131

Table 1.

Different PK parameters used in the clinical TDM of busulfan in children.

PK parameter (units) Equivalent value of the therapeutic range1
Css (ng/mL) 600 – 900
AUC (uM min) 900 – 1350
AUC (mg hr/L) 3.6 – 5.4
1

Equivalent values reflect the therapeutic range for a 6-hour dosing interval