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Properties of HYPE Dimers in Solution
(A) Analytical gel filtration of HYPE constructs. HYPE variant (103–434), containing TPR-motifs, linker, and FIC domain, is shown in red. HYPE (172–445), containing the linker helix and FIC domain, is shown in blue. The HYPE (103–445) L258D mutant is shown in black.
(B) Selected parameters of soluble HYPE constructs from analyzed SAXS data. See also Figure S4.
