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A Model Depicting HYPE Dimers in the Membrane Vicinity
Properties of HYPE structure are summarized by surface representation of a dimer. A HYPE dimer is featured relative to the plane of a cellular membrane, taking into consideration that the 20 amino acid long transmembrane domains would be imbedded into the membrane and that flexible (largely unstructured) linkers of about 60 residues connect transmembrane domains and TPR-motifs.
