Skip to main content
. Author manuscript; available in PMC: 2015 Feb 27.
Published in final edited form as: Circulation. 2013 Nov 18;129(2):145–156. doi: 10.1161/CIRCULATIONAHA.113.006641

Figure 3.

Figure 3

Spontaneous SR Ca2+-release events (SCaEs). A. Intracellular [Ca2+] (top) and membrane potential (bottom) in Ctl (left) and pAF (right) cardiomyocytes. SCaEs and delayed afterdepolarizations (DADs) were assessed during a one-minute follow-up period after cessation of 0.5 Hz-stimulation in 2.0-mmol/L extracellular-[Ca2+]. B. Prevalence of DADs exceeding 20 mV (left) and SCaEs (right). C. Intrinsic frequency of SCaEs (left), SCaE-amplitudes (middle) and corresponding membrane-potential changes (right). *P<0.05, **P<0.01 vs. Ctl. n/N=numbers of myocytes/patients. Comparisons using multi-level mixed-effects models.