FIGURE 1.

Adiponectin reduces HSC proliferation and α-SMA expression in vivo. fAd injection promoted no change in Sirius red (collagen) staining (10× magnification) (A), reduced HSC proliferation as determined by Ki67 (green) and α-SMA (red) co-staining (bar, 50 μm) DAPI (blue) (B), decreased α-SMA (light gray) expression (10× magnification) (C), and no change in apoptosis as determined by TUNEL (TUN; green) and α-SMA (red) co-staining (Bar, 50 μm) (D). The arrows indicate a light green colocalized cell, and the inset represents a 2× magnified double-labeled cell. *, p value <0.05.