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Response of S6K+/+, S6K1−/−, S6K2−/−, and S6K1−/− S6K2−/− mice to pathological and physiological stumuli. (A) Response to chronic exercise training (swimming for 4 weeks). *, P < 0.05 compared with non-swim. (B) Response to pressure overload (ascending aortic banding for 1 week). *, P < 0.05 compared with sham-operated mice.
