TABLE 1.

Relationship between plasma TMAO and aortic lesion area in mouse diversity panel

Plasma TMAO and aortic root atherosclerosis plaque extent quantified in female F1 progeny of the mouse diversity panel as described under “Experimental Procedures.” Data shown represent mean results and S.E. within the female F1 heterozygotes examined (cross between the indicated inbred background strain and homozygote C57BL/6-tg(Apob) mice. Strains appear in rank order of lesion area from least to greatest. Symbols shown correspond to the mouse strains plotted in Fig. 1.