FIGURE 1.

HDoHE formation in primary human airway epithelial cell cultures. Primary AEC were treated with vehicle control showing no endogenous HDoHE (A) 10 μm DHA for 2 h resulting in HDoHE formation monitored in the media (B). HDoHE regioisomers were quantified using 5-oxoETE-d₇ as an internal standard (C).