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. 2015 Jan 12;290(9):5868–5880. doi: 10.1074/jbc.M114.635151

FIGURE 6.

FIGURE 6.

15PGDH knockdown versus 15PGDH inhibition. A549 cells transfected with either 15PGDH shRNA or scramble shRNA were treated with 2 μm 14-HDoHE or PGE2 (ctrl) for 4 h. Scramble A549 cells were also treated with 50 μm CAY10397 (CAY). 14-oxoDHA (A) and 15-ketoPGE2 (B) formation was quantified. ***, p ≤ 0.001.