FIG. 5.

Clade-specific RTK expansion in the Ichthyosporea. The phylogenetic tree was inferred from the TK sequences of Creolimax (C) and Sphaeroforma (S). The family classification is represented by symbols. A typical structure of each family is shown at the bottom. Likely orthologous divergences of Creolimax and Sphaeroforma are labeled by black dots. One of the most parsimonious scenarios of domain architecture alteration was manually inferred based on the assumption that the ancestral gene belongs to the most dispersed RTK1 family. Red bars indicate branches where an architectural alteration is assumed. The full figure with bootstrap values and domain architectures is in supplementary figure S9, Supplementary Material online.