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Human metapneumovirus (HMPV) 54G10 monoclonal antibody–resistant mutant (MARM). A, The 50% inhibitory concentration of 54G10 for the HMPV MARM is >100 µg/mL. Bars represent the standard error of the mean from 2 independent experiments performed in triplicate. B, The escape mutant sequence has a valine to glycine mutation at amino acid 397 and a glutamine to histidine mutation at amino acid 434. Mutations are not present in other HMPV sequences.
