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. 2015 Feb 25;16(1):23. doi: 10.1186/s13059-015-0590-8

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© Hubbard et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Polymorphic and differentially expressed effector candidates can be linked to the virulence profiles of the PST 2013 field isolates. (a) Polymorphism analysis highlights cluster-specific effector candidates. Circles represent the number of genes with non-synonymous mutations in each category. (b) Differential expression analysis identifies cluster-specific differentially expressed effector candidates. Roman numerals represent population clusters. (c) PST130_08031 is a previously identified effector candidate that was significantly down-regulated by isolates in cluster III and had two amino acid substitutions that were specific and conserved among cluster I isolates. The five carboxy-terminal amino acids were not defined due to poor coverage.