Figure 2.

Differences in aqueous serum metabolite concentrations between l-carnitine- and placebo-treated patients with septic shock. (A) Carnitine (*P < 0.001), (B) acetylcarnitine (*P < 0.001; ⁺P = 0.001), and (C) creatinine (*P = 0.008; ⁺P = 0.050) levels were different at 24 and 48 hours and (D) malonate (*P = 0.002) and (E) methionine (*P = 0.032) levels were different at 24 hours. There were no differences in metabolite concentrations between the two groups at T0 (before treatment). Data represent medians ± the interquartile range of 11–16 l-carnitine- and placebo-treated patients at each time point.