Table 1.

Models

Model ID	B1	B2	B3	B4	B5	B6
Model Ref	[25]	[23]	[24]	[26]	[27]	[29]
Cell	S. cerevisiae	E. coli	E. coli	CHO	Generic	Drosophila
						melanogaster
Description	Metabolic:	Metabolic:	Metabolic: CCM	Metabolic	Signal	Developmental
level	genome scale	CCM	& transcription		transduction	GRN (spatial)
Parameters	1759	116	178	117	86	37
Dynamic states	276	18	47	34	26	108 –212
Observed states	44	9	47	13	6	108 –212
Experiments	1	1	1	1	10	1
Data points	5280	110	7567	169	96	1804
Data type	simulated	measured	simulated	simulated	simulated	measured
Noise level	σ=5%	real	no noise	variable	σ=5%	real

Main features of the benchmark models. The standard deviation, σ, is given in those cases where artificial noise with constant variance was added to the data.