Table 6.
Univariate and multivariate analyses of prognostic factors for overall survival
| Variable |
Univariate analysis |
Multivariate analysis |
||
| HR (95%CI) | P value | HR (95%CI) | P value | |
| Splenectomy | 0.862 (0.497-1.492) | 0.595 | ||
| Gender, F | 0.466 (1.125-4.083) | 0.020 | 0.774 (1.164-4.041) | 0.015 |
| Age, > 60 yr | 0.876 (0.384-1.998) | 0.752 | ||
| HBsAg, positive | 0.552 (0.259-1.176) | 0.124 | ||
| AFP, > 400 ng/mL | 0.986 (0.563-1.728) | 0.962 | ||
| Platelet count | 1.004 (0.995-1.013) | 0.397 | ||
| White blood cell count | 0.975 (0.901-1.055) | 0.533 | ||
| Tumor number, multiple | 2.216 (1.033-4.752) | 0.041 | 0.801 (1.071-4.633) | 0.032 |
| Tumor size, > 5 cm | 2.067 (1.087-3.930) | 0.027 | 0.572 (0.991-3.169) | 0.054 |
| Micro-vascular invasion | 0.624 (0.329-1.182) | 0.148 | ||
| Recurrence | 14.376 (6.233-33.160) | < 0.001 | 2.344 (4.961-21.882) | < 0.001 |
HBsAg: Hepatitis B surface antigen; AFP: Alpha-fetoprotein.