Table 2.
Vaccine-protected RM (Undetectable viremia) | Challenge virus | Virus-specific immune responses (week 0) | Ref | |
---|---|---|---|---|
Cellular IFN-γ ELISPOT (Total SFU/106 PBMC) | Humoral Challenge virus-specific nAb titer (IC50, TZM-bl assay) | |||
RAt-9 | SHIV-1157ip (tier 1) | 3830 | 130 | 32 |
RRi-11 | SHIV-1157ipEL-p (tier 1) | 3560 | 3157 | 13 |
RTr-11 | SHIV-1157ipEL-p (tier 1) | 920 | 4382 | 13 |
RQe-10 | SHIV-1157ipEL-p (tier 1) | 520 | 48 | 12 |
ROb-12 | SHIV-2873Nip (tier 2) | 570 | <20 | Present study |