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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2014 Sep 28;20(12):1975–1981. doi: 10.1016/j.bbmt.2014.08.013

Table 3. Transplant outcomes for all patients.

All patients By donor type
Measure N=227 MRD (N=87) MUD (N=108) Haplo (N=32)

Day 30 chimerism

Donor engraftment

n 216, 87 98 31,

n (%) 210 (97) 86 (99) 94 (96) 30 (97) 0.441a

100% donor

n 208, 85, 93, 30,

n (%) 204 (98) 84 (99) 90 (97) 30 (100) 0.798a

CMV reactivation

n 224 87 106 31

n (%) 121 (54) 42 (48) 57 (54) 22 (71) 0.098a

EBV reactivation 0 0 0 0 -

CI aGVHD 2-4 (%) Day 100 30 31 29 29 0.709b

CI aGVHD 3-4 (%) Day 100 7 11 6 0 0.044b

CI cGVHD (Ext+Lim) (%) Year 3 34 43 30 19 0.094b

CI cGVHD (Ext) (%) Year 3 24 31 21 11 0.125b

Follow-up survivors Median (range), mo 31 (0.8–85.4) 45 (6.4-78.8) 40 (0.8-85.4) 13 (1.6-31.2) <0.001c

CI Relapse (%) 0.750b
Day 100 8 7 8 10
4 0 0
Year 1 26 28 23 33

CI Non-relapse mortality (%) 0.099b
Day 100 18 10 26 13
Year 1 27 20 35 24

Progression free survival (%) 0.120d
Day 100 74 83 65 78
Year 1 46 52 42 43
Year 3 31 36 27 30
Median (95% confidence interval) days 284 (215, 404) 411 (237, 757) 238 (160, 386) 276 (173, NE)

10/10 10/10 5/10

a: acute; c: chronic; CI: cumulative incidence; CMV: cytomegalovirus; EBV: Epstein-Barr virus; CR: complete remission; ext: extensive; haplo: haploidentical donor; lim.: limited; Mel: melphalan; mo: month; MRD: matched related donor; MUD: matched unrelated donor;, n: number; NE = not estimable;

a

: Fisher's exact test.

b

: Gray's test.

c

: Kruskal-Wallis test.

d

: Log-rank test.