Fig. 1.

 Alignment and swap mutants of C elegans Hsp12.2 and human αB-crystallin. (A) Alignment of Hsp12.2 and αB-crystallin. Identical residues are in black and similar residues in gray. The demarcation of domains is according to Leroux et al (1997b) and de Jong et al (1998). (B) Schematic representation of domains in αB-crystallin (open bars, uppercase N-C-T), Hsp12.2 (gray bars, lowercase n-c-t), and their swap mutants. Numbers indicate residue positions in the proteins. N,n: N-terminal domain; C,c: C-terminal domain; T,t: C-terminal tail. Note that t consists of only 1 residue