Fig 3. Comparison between fasting insulin level, IS (HOMA-index and Matsuda-ISI) as well as insulin secretion (insulin-iAUC, insulin-tAUC/glucose-tAUC, Stumvoll-index) at baseline (T0), after caloric restriction (CR, T2) and refeeding (RF, T3).

*p<0.05, **p<0.01, ***p<0.001; Repeated measures ANOVA with Bonferroni adjustments. HOMA, homeostasis model assessment; ISI, insulin sensitivity index, iAUC, incremental area under the curve; tAUC, total area under the curve