Table 1. Impaired increase of the ABAp during OGTT in T2D patients.
| NGT | T2D | p | |
|---|---|---|---|
| N | 7 | 9 | |
| Age (years) | 58.1±6.2 | 60.2±10.2 | 0.642 |
| BMI (kg/m 2) | 30.2±6.1 | 27.7±4.4 | 0.342 |
| FPG (mg/dL) | 95.4±12.6 | 145.8±39.6 | 0.007 |
| Fasting ABAp | 0.97±0.36 | 1.75±1.02 | 0.040 |
| (nM) | 0.99 (0.38–1.54) | 1.61 (0.35–3.42) | |
| ABA AUC (nmol/L*min) | 121.7±33.9 | 68.3±44.3 | 0.019 |
| Glucose AUC (mg/dL*min) | 18550±4422 | 30694±6129 | <0.001 |
| Insulin AUC (mU/L*min) | 6998±910 | 8192±2724 | 0.155 |
Study participants underwent an OGTT after overnight fasting. Plasma ABA, glucose and insulin concentrations were measured immediately before and 15, 30, 60, 90 and 120 min after the ingestion of 75 g of glucose. AUCs were calculated from the absolute values for glycemia and insulinemia, or from the values relative to time zero for ABAp. Data are presented as mean±SD and were compared by unpaired t-test (significant p values in bold). For ABAp, median value and range are also shown.