Table 3.

Adipose Cell Size Parameters in Insulin Resistant versus Insulin Sensitive Subgroups of Overweight/Moderately-obese Adults

	Insulin Sensitive (n=55)	Insulin Resistant (n=74)	p-value	p-value-adja
% Body Fat	40.0 ± 5.7	40.0 ± 6.2	0.99	0.09
Sex (F/M)	39/16	39/35	0.03	---
% small cells	50 ± 12	56 ± 11	0.004	0.002
% large cells	50 ± 12	44 ± 11	0.004	0.002
Peak diameter	109 ± 17	114 ± 13	0.07	0.01
Mean diameter	70 ± 9	71 ± 9	0.47	0.74
Total body cell numberb	1.14E11 ± 5.55E10	1.17E11 ± 4.41E10	0.78	0.41
Total body small cell numberb	5.88E10 ± 2.46E10	6.56 ± 3.22E10	0.27	0.71
Total body large cell numberb	5.48E10 ± 2.4E10	4.77E10 ± 1.66E10	0.06	<0.001
Ratio total small to large cells	1.13 ± 0.50	1.46 ± 0.74	0.004	0.002

^aadjusted for % body fat, sex

^bestimated for total body based on fat mass and average cell volume