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. Author manuscript; available in PMC: 2016 Mar 15.
Published in final edited form as: Mol Cell Endocrinol. 2014 Aug 27;404:1–8. doi: 10.1016/j.mce.2014.07.024

Fig. 3.

Fig. 3

Levels of endogenous production of melatonin and its metabolites depend on race, age and gender. Epidermis was extracted with 75% acetonitrile after homogenizing and applied to qTOF LC-MS (EIC) for quantification using corresponding standards (m/z = 233.1 [M+H]+ for melatonin; 287.1 [M+K]+ for 6(OH)M; 287.1 [M+Na]+ for AFMK, and 174.1 [M+H-NH3]+ for 5MT). *, p < 0.05; ***, p < 0.001 at Student t-test and #, p < 0.05 at Mann–Whitney test. Black (African-Americans) and white (Caucasians): race comparison; Age: age comparison; Sex: male and female comparison.