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. 2003 Oct 24;19(1):324–331. doi: 10.2119/molmed.2013.00034

Figure 5.

Figure 5

The proposed mechanism of action of APC on RSFs, as shown in this study. RSF proliferation contributes to inflammation, which further promotes a cyclic perpetuation in RA. APC acts on signaling molecules that inhibit both RSF proliferation and inflammation.