Figure 5. Treating obesity decreases TNF-α levels in the obesity-related asthma model.

DIO mice performed voluntary exercise or consumed a normal chow diet to treat obesity. TNF-α levels in the lung homogenates were measured in the weight-reduced, obesity-related asthma mice. The solid lines indicate statistical significance between each group (p<0.05). Error bars indicated mean±SEM of five mice per group. All data are representative of three independent experiments.