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. 2015 Jan 22;43(4):2188–2198. doi: 10.1093/nar/gku1394

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 9. — Molecular validation of predicted LINE–LINE CNVs identified among healthy individuals by array CGH. (A) Array CGH data indicates a CNV at 2q34 in subject 1 or 2. (B) Schematic representation of the L1PA elements that mediate the CNV and LR-PCR primers testing for the CNV. (C) LR-PCR identifies the presence of a deletion in subject 1. (D) Array CGH data indicates a CNV at 8p23.3 in subject 1 or 2 and subject 5 or 6. (E) Schematic representation of the L1PA elements that mediate the CNVs and LR-PCR primers testing for the CNVs. (F) LR-PCR identifies the presence of homozygous duplications in subjects 1 and 5.