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. 2015 Jan 23;7(2):219–237. doi: 10.3390/toxins7020219

Table 6.

Structures of natural peptides and their cationicity-/amphipathicity-enhanced analogues.

Peptide Primary structure Mass (Da)
AaeAP1 FLFSLIPSVIAGLVSAIRNamide 2016.18
AaeAP2 FLFSLIPSAIAGLVSAIRNamide 1986.15
AaeAP1a FLFKLIPKVIKGLVKAIRKamide 2209.48
AaeAP2a FLFKLIPKAIKGLVKAIRKamide 2181.45
  *  * *  *  *

* Sites of cationicity enhancement using lysyl (K) residue substitution for Ser(S)4, Ser(S)8, Ala(A)11 Ser(S)15 and Asn(N)19. Net positive charge increase from +2 (natural peptides) to +7 (respective analogues).